Detecting biological threats in the field by holographic microscopy using deep learning


HoloZcan provides a new tool for public safety actors (police, rescue workers, disaster managers, crisis managers, critical infrastructure security actors and service providers) especially in terms of autonomous detection and response.

Funded by the European Union’s Horizon 2020 research and innovation program, the HoloZcan Consortium is coordinated by Ideas Science Ltd (Hungary) and brings together nine organizations from five different EU countries.

The project will increase the bioaerosol (environmental and exhaled) detection and measurement capacity of CBRN practitioners by developing a highly portable, high-resolution, high-throughput automatic detection system to perform automatic classification of pathogens and particles.

HoloZcan develops novel holographic microscopy and imaging technology for rapid and cost-effective screening of potential biological threats and unknown potentially hazardous substances, combined with artificial intelligence and machine learning methods. It provides the framework for a dynamic feature selection and validation algorithm to increase the system’s capacity for continuous innovation in adaptive learning and database optimization for specific bioinformatics applications. The project also develops comprehensive and innovative means of sampling respiratory, ventilation and environmental biological data that can be used in real time, remotely or in a mobile biosensing context.

As a Partner, DMI Associates will play a major role in the project, thanks to the involvement of Carine BERNY and Michel ZAYET whose contribution will be crucial for the elaboration of a Communication and Diffusion plan, in addition to the Training and the involvement of the Users allowing to conceive a final product with a Commercial potential.

The project builds on the versatility of the HoloZcan technique for a wide range of applications and demonstrates its technical feasibility. The project addresses the real needs of European practitioners and the technology gaps identified by the ENCIRCLE project as outlined in the ENCIRCLE Technology Catalogue and addresses several shortcomings of current approaches to biothreat agent detection.

The HoloZcan project applies an adaptive and flexible approach to design, and CBRN practitioners are involved as project stakeholders in the process. 

More details here:  







field of expertise



4 380 400 €


EU Horizon 2020


IDEAS Science, DMI, Institut Pasteur, Polimi, University of Lodz, Metropolitan Police W., SIOUX, ZUGMED, DataSense Lab

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